It Is Possible to Reverse Sexes!

Well today I heard a really bizarre lecture at the ASRM annual meeting in Atlanta.  Robin Lovell-Badge from the stem cell bio branch of UK National Institute for medical Research reported new genetic finds that gonadal sex in mammals is potentially reversible after birth!

It has been known that to make a testicle the male genes SRY and SF1 are required.  He has now discovered that there are similar genes that regulate female ovary development — namely FOXL2 and beta-catenin.

Just reported is that in the MOUSE–genetic manipulation can turn these genes on and off even after birth.  The results?  An ovary became a testicle!!  Once again genetics is blowing away notions of biology and gender that were never questioned before.

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