New Drugs Enhance Performance, Eliminate Need to Sleep

crank_poster.jpgthis stuff makes crank look like candy

Gizmag reports on the further evolution of no-sleep performance enhancing drugs.

The original version of these substances was the “time-shifting” drug, Modafinil that enables you to stay awake for 40+ hours with close to full mental capacity and with few side effects. (produced by Cephalon as PROVIGIL®, MODIODAL® in France and VIGIL® in Germany, for excessive sleepiness associated with narcolepsy and for “shift work sleep disorder” – hear that you medical interns?- web site advertises free 7 day trial supply).  

This is precisely the substance the the former chief medical director of the olympic committee spoke to me of.  He asked – once this stuff hits the street don’t you think a majority of college students would use it to perform better on exams?   The military sure thinks its a god idea for soldiers and pilots.  You can read my thoughts on how far people will go in the future to enhance their bodies hereIf you think plastic surgery is the rage of body enhancement – wait until we get performance enhancing bionics and cognitive enhancing drugs and implants!

The drug is a eugeroic and offers improved memory, mood enhancement, improved alertness and cognitive powers without any of the nasty side effects and mass murder of speed and crank.

What’s a Eugeroic you ask?  - Literally the term means “Good Arousal” .  They are a class of novel stimulants that produce long-lasting mental arousal. They are unique in producing hypervigilence and alertness without peripheral effects or addidition of usual stimulants.  Strangely, they have minimal effect on sleep structure, and do not cause rebound hypersomnolence (crashing).

You might also be interested in Ampakines are similar but also cause memory enhancement (just a bit of abuse potential there).  One of these – a drug code-named CX717 from Cortex – reportedly enabled sleep deprived rhesus monkeys to outperform rested normal monkeys on memory tasks. 

Under carefully controlled conditions and constant medical monitoring, the monkeys were individually sleep-deprived for 30-36 hours and re-tested at that time. When monkeys are sleep deprived their performance accuracy is reduced by 15-25%, and their reaction times slow by at least 50%. A dose of 0.8 mg/kg of CX717 completely reversed the performance deficits associated with sleep-deprivation. In addition, specific brain EEG changes that occur after sleep deprivation were returned to the non-sleep-deprived state in the CX717 group, but not in the control group. Thus, CX717 counteracted the effects of periods of prolonged sleep deprivation when given immediately before testing  

Not surprisingly, DARPA had a hand in these experiments.

Man, I remember as an intern a 43 hour shift I once did (Friday AM straight to Monday afternoon).  By Sunday I was practically hallucinating, everthing was in slow motion , and there was a constant sound of running water…  I predict these drugs have an abuse potential greater than any drug since alcohol.

I hear there is a new super eugeroic called armodafinil coming down the pike with even more potent effects.

Share

15 thoughts on “New Drugs Enhance Performance, Eliminate Need to Sleep

  1. Holy cow – I had a patient come in with a work injury at 0300. “Provigil” was one of her medications. When I asked her what it was for, she said “I work night shift.” Uh….okay……

    I don’t even want to think what I could accomplish in 40 hours with no sleep…the temptations would be too great.

    Somewhere, somehow, this has to be bad….

  2. Good Night Sleep

    Lack of sleep can result in stress, lack of concentration, moodiness, memory loss, lower motivation and fatigue. It is important to get a good night sleep otherwise it may lead to different sleep disorders. More than eighty percent of people suffering from depression are suffering with sleep problems.

    At present, one of the most common problems is Sleep deprivation. In fact the Better Sleep Council surveyed a thousand adult respondents and discovered that more than 30% of them confessed to not getting enough sleep each night.

    Here are 101 ways to get good night sleep for those who experience difficulty in getting sleep.

    http://www.sleepdisordersguide.com/blog/good-night-sleep-101-ways/

  3. How can I get my doctor to prescribe this medicine? I guess I say I work shift work and need help staying awake? What a great drug!

  4. Pingback: staying awake for sleep deprived eeg

  5. Pingback: docinthemachine » Post Topic » Top Scientists Using Performance Enhancing Drugs

  6. I’ve always for as long as I can remember felt sleepy or tired, even when young. I was always the one who fell asleep in the deer blind or while driving etc… Being the case I started using meth in college and used it on and off for 20 years. Problem it made me short tempered and horny as hell, ended up getting divorce at 42. I stopped using and I still battle fatigue daily. Asked my Doc about Provigil after reading about it in a mag. As far as I can tell it seems to work okay but had to increase dose. I can get too wired and the crash or hangover is no different from crank, maybe even worse. You still get a craving when coming off after about ten or twelve hours. If you take more you will stay awake but feel like you’ve been beat with a stick, ache all over, head ache, sore muscles, shakes. At this point more pills won’t help, just makes you sick. After finally sleeping good all night you feel normal next day but still have a tolerance to the pills. I don’t see a problem with long term addiction but a person might take months supply in two weeks. I think it could possibly lead to illegal drug use if a person was familiar with the drug scene and knew how and where to look for an illegal substitute. So there you go baseball fans, that’s the scoop on Provigil.

  7. Pingback: docinthemachine Post Topic New Drugs Enhance Performance | Insomnia Cure

  8. Pingback: Eugeroic drug | Sekun

Leave a Reply

Your email address will not be published. Required fields are marked *

*

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>