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	<title>Comments on: Live to be 100? DITM Tells You How</title>
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	<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/</link>
	<description>transforming medicine with tomorrow’s technology</description>
	<pubDate>Wed, 07 Jan 2009 02:32:56 +0000</pubDate>
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		<title>By: Dr. Leonid Gavrilov, Ph.D.</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-9814</link>
		<dc:creator>Dr. Leonid Gavrilov, Ph.D.</dc:creator>
		<pubDate>Wed, 18 Apr 2007 20:08:02 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-9814</guid>
		<description>Thank you for your interesting post!
I thought perhaps you may find it interesting to take a look at the original published peer-reviewed study:
&lt;a href="http://longevity-science.blogspot.com/2007/02/naaj-paper.html" rel="nofollow"&gt;Longevity Science: NAAJ Paper&lt;/a&gt;
&lt;a href="http://longevity-science.blogspot.com/2007/02/naaj-paper.html" rel="nofollow"&gt;http://longevity-science.blogspot.com/2007/02/naaj-paper.html&lt;/a&gt;</description>
		<content:encoded><![CDATA[<p>Thank you for your interesting post!<br />
I thought perhaps you may find it interesting to take a look at the original published peer-reviewed study:<br />
<a href="http://longevity-science.blogspot.com/2007/02/naaj-paper.html" rel="nofollow">Longevity Science: NAAJ Paper</a><br />
<a href="http://longevity-science.blogspot.com/2007/02/naaj-paper.html" rel="nofollow">http://longevity-science.blogspot.com/2007/02/naaj-paper.html</a></p>
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		<title>By: More on Longevity and Telomeres- Answers from the Researcher &#187; docinthemachine</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-610</link>
		<dc:creator>More on Longevity and Telomeres- Answers from the Researcher &#187; docinthemachine</dc:creator>
		<pubDate>Sun, 10 Dec 2006 22:16:26 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-610</guid>
		<description>[...] I recently posted on the new research linking telomere length (telomeres are the protective end caps on DNA) to human longevity.  This information came from a leading fertility researcher Dr. David Keefe who has discovered the link between telomeres and human egg and embryo health.  This is a major development that I have called the &#8220;unified theory of reproductive aging&#8221;.  It explains longevity, miscarriages, age related declines in fertility among others. I had a wave of questions emailed to me so I asked Dr. Keefe to elaborate and clarify some of the most common questions.  Here is what he said: 1)     I do not understand why repair mechanisms (telomerase etc) do not correct the damage in the adult organism.  If it is true that the offspring of an older egg is destined to have short telomeres why is this not repaired?  Do the necessary enzymes not exist in the adult cell?  You showed me that there is a repair mechanism in some cells &#8212; why does this not fix the problem always? Very few tissues express telomerase.   Stem cells and cancer cells are the only tissues which express telomerase.  Eggs and preimplantation embryos, to the blast stage, also do not express appreciable levels of telomerase activity. [...]</description>
		<content:encoded><![CDATA[<p>[&#8230;] I recently posted on the new research linking telomere length (telomeres are the protective end caps on DNA) to human longevity.  This information came from a leading fertility researcher Dr. David Keefe who has discovered the link between telomeres and human egg and embryo health.  This is a major development that I have called the &#8220;unified theory of reproductive aging&#8221;.  It explains longevity, miscarriages, age related declines in fertility among others. I had a wave of questions emailed to me so I asked Dr. Keefe to elaborate and clarify some of the most common questions.  Here is what he said: 1)     I do not understand why repair mechanisms (telomerase etc) do not correct the damage in the adult organism.  If it is true that the offspring of an older egg is destined to have short telomeres why is this not repaired?  Do the necessary enzymes not exist in the adult cell?  You showed me that there is a repair mechanism in some cells &#8212; why does this not fix the problem always? Very few tissues express telomerase.   Stem cells and cancer cells are the only tissues which express telomerase.  Eggs and preimplantation embryos, to the blast stage, also do not express appreciable levels of telomerase activity. [&#8230;]</p>
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		<title>By: More on Longevity and Telomeres- Anwers from the Researcher &#187; docinthemachine</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-609</link>
		<dc:creator>More on Longevity and Telomeres- Anwers from the Researcher &#187; docinthemachine</dc:creator>
		<pubDate>Sun, 10 Dec 2006 22:14:30 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-609</guid>
		<description>[...] I recently posted on the new research linking telomere length (telomeres are the protective end caps on DNA) to human longevity.  This information came from a leading fertility researcher Dr. David Keefe who has discovered the link between telomeres and human egg and embryo health.  This is a major development that I have called the &#8220;unified theory of reproductive aging&#8221;.  It explains longevity, miscarriages, age related declines in fertility among others. I had a wave of questions emailed to me so I asked Dr. Keefe to elaborate and clarify some of the most common questions.  Here is what he said: 1)     I do not understand why repair mechanisms (telomerase etc) do not correct the damage in the adult organism.  If it is true that the offspring of an older egg is destined to have short telomeres why is this not repaired?  Do the necessary enzymes not exist in the adult cell?  You showed me that there is a repair mechanism in some cells &#8212; why does this not fix the problem always? Very few tissues express telomerase.   Stem cells and cancer cells are the only tissues which express telomerase.  Eggs and preimplantation embryos, to the blast stage, also do not express appreciable levels of telomerase activity. [...]</description>
		<content:encoded><![CDATA[<p>[&#8230;] I recently posted on the new research linking telomere length (telomeres are the protective end caps on DNA) to human longevity.  This information came from a leading fertility researcher Dr. David Keefe who has discovered the link between telomeres and human egg and embryo health.  This is a major development that I have called the &#8220;unified theory of reproductive aging&#8221;.  It explains longevity, miscarriages, age related declines in fertility among others. I had a wave of questions emailed to me so I asked Dr. Keefe to elaborate and clarify some of the most common questions.  Here is what he said: 1)     I do not understand why repair mechanisms (telomerase etc) do not correct the damage in the adult organism.  If it is true that the offspring of an older egg is destined to have short telomeres why is this not repaired?  Do the necessary enzymes not exist in the adult cell?  You showed me that there is a repair mechanism in some cells &#8212; why does this not fix the problem always? Very few tissues express telomerase.   Stem cells and cancer cells are the only tissues which express telomerase.  Eggs and preimplantation embryos, to the blast stage, also do not express appreciable levels of telomerase activity. [&#8230;]</p>
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		<title>By: V</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-536</link>
		<dc:creator>V</dc:creator>
		<pubDate>Fri, 08 Dec 2006 03:26:19 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-536</guid>
		<description>Great!  My mom had me at 39 &#38; I had my son at 40.  One more thing to worry about :^0</description>
		<content:encoded><![CDATA[<p>Great!  My mom had me at 39 &amp; I had my son at 40.  One more thing to worry about :^0</p>
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		<title>By: Kim</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-511</link>
		<dc:creator>Kim</dc:creator>
		<pubDate>Wed, 06 Dec 2006 05:52:19 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-511</guid>
		<description>&lt;i&gt;I'm&lt;/i&gt; freaking out over the possibilities here! LOL!  But I have to tell you the first thing that caught my eye was having a Mom under 25...mine was 17 when I was born so I have at least another 50 years!  : D

Very, very amazing stuff....a bit over my head, but not so much that I can't understand the ramifications....</description>
		<content:encoded><![CDATA[<p><i>I&#8217;m</i> freaking out over the possibilities here! LOL!  But I have to tell you the first thing that caught my eye was having a Mom under 25&#8230;mine was 17 when I was born so I have at least another 50 years!  : D</p>
<p>Very, very amazing stuff&#8230;.a bit over my head, but not so much that I can&#8217;t understand the ramifications&#8230;.</p>
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		<title>By: Grand Rounds 3.11 Are Up &#187; docinthemachine</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-509</link>
		<dc:creator>Grand Rounds 3.11 Are Up &#187; docinthemachine</dc:creator>
		<pubDate>Wed, 06 Dec 2006 02:52:50 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-509</guid>
		<description>[...] I am delighted that she chose to include my post on How to live to be 100- DITM &#38; a fertility genetics study shows you how!  (Hint- the answer is all in the telomeres- they are aglets of DNA) [...]</description>
		<content:encoded><![CDATA[<p>[&#8230;] I am delighted that she chose to include my post on How to live to be 100- DITM &#38; a fertility genetics study shows you how!  (Hint- the answer is all in the telomeres- they are aglets of DNA) [&#8230;]</p>
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		<title>By: Michele</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-492</link>
		<dc:creator>Michele</dc:creator>
		<pubDate>Sun, 03 Dec 2006 22:08:16 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-492</guid>
		<description>I'm with Chris...a fascinating and excellent post.  I can't believe people aren't freaking out more over the possibilities here.  Soon enough, they will...

Michele</description>
		<content:encoded><![CDATA[<p>I&#8217;m with Chris&#8230;a fascinating and excellent post.  I can&#8217;t believe people aren&#8217;t freaking out more over the possibilities here.  Soon enough, they will&#8230;</p>
<p>Michele</p>
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		<title>By: Chris</title>
		<link>http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-449</link>
		<dc:creator>Chris</dc:creator>
		<pubDate>Wed, 29 Nov 2006 17:30:07 +0000</pubDate>
		<guid isPermaLink="false">http://docinthemachine.com/2006/11/28/live-to-be-100-ditm-tells-you-how/#comment-449</guid>
		<description>This is really facinating.  Thank you for taking the time to write it up.  If it is really true, and I tend to believe it is, I hope I live long enough to take advantage of it.  I've been following the Geron company for many years and I really think they are onto something big.
(If you aren't already aware this post made it to the Google Finance GERN blog posts section...
http://www.google.com/finance?client=ig&#38;q=GERN)</description>
		<content:encoded><![CDATA[<p>This is really facinating.  Thank you for taking the time to write it up.  If it is really true, and I tend to believe it is, I hope I live long enough to take advantage of it.  I&#8217;ve been following the Geron company for many years and I really think they are onto something big.<br />
(If you aren&#8217;t already aware this post made it to the Google Finance GERN blog posts section&#8230;<br />
<a href="http://www.google.com/finance?client=ig&amp;q=GERN" rel="nofollow">http://www.google.com/finance?client=ig&amp;q=GERN</a>)</p>
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